Director Marc Levin travels to Chicago with hip-hop legend Chuck D (of Public Enemy) and Marshall Chess (son of Leonard Chess and heir to the Chess Records legacy) to explore the heyday of Chicago blues as they unite to produce an album that seeks to bring veteran blues players together with contemporary hip hop musicians. Along with never-before-seen archival footage of Howlin' Wolf, Muddy Waters and the Paul Butterfield Blues Band, are original performances by Koko Taylor, Otis Rush, Magic Slim, Ike Turner, and Sam Lay.